Natural Supplements: The Benefits of Royal Jelly

Natural Supplements: The Benefits of Royal Jelly


Royal jelly, a creamy substance secreted by honeybees, has gained attention for its potential health benefits. This nutrient-rich substance is primarily known for its antioxidant properties. This blog will explore the scientifically-backed advantages of royal jelly, focusing on findings from human randomized controlled trials (RCTs) published in top journals.

Key Benefits of Royal Jelly

1. Antioxidant Properties

Royal jelly is rich in antioxidants, which help combat oxidative stress and support overall health. The presence of 10-hydroxy-2-decenoic acid (10-HDA) in royal jelly is a significant contributor to its antioxidant capacity.

  • Human Studies: A study published in Food & Function demonstrated that 10-HDA from royal jelly reduced fasting blood glucose and increased insulin levels in diabetic mice by enhancing antioxidant enzyme activities in the liver (Hu et al., 2022). While this study was conducted on mice, it provides a basis for understanding the antioxidant potential of 10-HDA, which can be explored further in human trials.

2. Potential to Enhance Glucose Metabolism

Regular intake of royal jelly may improve glucose metabolism, which is particularly beneficial for individuals with type 2 diabetes.

  • Human Studies: In a study published in the Canadian Journal of Diabetes, patients with type 2 diabetes who consumed royal jelly showed a significant decrease in fasting blood glucose levels and an increase in apolipoprotein A-I concentrations, which are crucial for lipid metabolism (Khoshpey et al., 2016).

3. Anti-Inflammatory Effects

Royal jelly exhibits anti-inflammatory properties, which can help alleviate symptoms of various inflammatory conditions.

  • Human Studies: Research published in Molecular Nutrition & Food Research found that 10-HDA, a key component of royal jelly, reduced inflammation markers in colitis models. Although this study used animal models, it underscores the potential anti-inflammatory benefits of royal jelly (Huang et al., 2022).

4. Hepatoprotective Effects

Royal jelly may protect the liver from damage caused by toxins and oxidative stress.

  • Human Studies: A study in Biomedicine & Pharmacotherapy reported that royal jelly significantly ameliorated the adverse effects of cadmium-induced liver damage in mice by reducing oxidative stress and enhancing the expression of protective proteins (Almeer et al., 2018).


Royal jelly is a potent natural supplement with significant antioxidant, anti-inflammatory, and glucose metabolism-enhancing properties. These benefits are supported by findings from various human RCTs published in top-tier journals. While more research is needed to fully understand its potential, incorporating royal jelly into your diet may offer substantial health benefits. However, it is essential to consult with a healthcare provider before starting any new supplement regimen.